They do see: Algiman M, Dietrich G, Nydegger Ue, Boieldieu D, Sultan Y,
Kazatchkine Md. 1992. Natural antibodies to factor VIII (anti-hemophilic
factor) in healthy individuals. Proceedings of the National Academy of
Sciences of the United States of America. 89: 3795-9
Jeff Frelinger
Indeed antibodies to Factor VIII and IX are a problem clinically (called
inhibitors)
Jeff Frelinger