I wonder whether anyone would kindly tell me what proportion B cells
is in adult mouse spleen single cell suspension? This sounds a very
simple question, but I find it difficult to get a straight answer from
standard textbooks. In Cellular and Molecular Immunology (2nd edition)
by Abbas et al., it says B lymphocytes form 40-45% of total
lymphocytes in the spleen (human or mouse, not specified). But then
what proportion total lymphocytes make in the entire spleen cell
population? - No answer on that. In Basic and Clinical Immunology (7th
edition) by Stites et al., it says B cells make up 40% of lymphocytes
in spleen marginal zone-white pulp, but again not the information I
would like to have. Perhaps it is too simple that no one cares any
more to know about. Thanks for any help in advance.
Yiu-Loon Chui, Ph.D
Clinical Immunology Unit
Chinese Univeristy of Hong Kong
