IUBio

Firestorm/Transformation

John Cherwonogrodzky jcherwon at dres.dnd.ca
Wed Mar 13 16:17:14 EST 1996


Dear Colleagues:
      My apologies for the following very speculative association.
      By chance I read 2 postings, one was on the the transition of HIV 
patients from AIDS negative to AIDS positive symptoms where the latter is 
eventually overwhelmed by HIV infection. The other was on transformation of 
bacilli and it brought back memories of competency and transformation taught 
by Dr. Pakula, one of the discoverers of this biological trait. Are the two 
related?
     Genetic mutations occur on a regular basis. Does the body have a 
mechanism of competency/transformation in which it regularly checks its 
genetic make-up? Essentially this would be a type of genetic integrity by 
cellular consensus. This might explain other phenomena such as centripetal 
infection (e.g. rabies), ageing (if competency is regulated by a hormone, 
shutting down this hormone would shut down cellular consensus), increased 
rate of Down's syndrome for elderly women, and the development of AIDS 
(RNA -> DNA ->lysogeny, genetically overwhelming the system).
     Comments?....John   



More information about the Immuno mailing list

Send comments to us at biosci-help [At] net.bio.net