dspinella at chugaibio.com
Fri Dec 12 10:52:31 EST 1997
> What determines Rh + or - phenotype? Is it a simple dominant vs.
> recessive trait or something more complex?
Actually, its quite bit more complicated than that. There are three Rh
antigens (D Cc, and Ee) and two alternatively spliced structural genes
(RHD and RHCE). For a good review, see JP Cartron, "Defining the Rh
blood group antigens. Biochemistry and Molecular Genetics" Blood Rev. 8:
199-212 (1994). Cheers. -- Dom Spinella
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