Doug Pecota wrote:
>> I can think of three reasons phage have not been used for controlling
> bacteria in the clinic.
> 1. By the time you have isolated the phage and shown it to be safe
> bacteria that are resistant to it will already be present in the
> population.
what about a phage cocktail of sorts, for things like bacterial dysyntery or
cholera?
> 2. The host range of many phage is very narrow so it is likely to be
> effective against a narrow spectrum of bacteria and only useful for
> digestive track ailments.
what about genetically engineering phage to be multi-specific?
> 3 It is very cheap to make phage. One could easily make enough phage
> in a lab to supply the world wide needs. It also may not be possible to
> obtain exclusive rights for its use so it may not be that profitable.
Now that do present a sticky wicket for the pharm co's!
But what about animals and plants?
>> Hope this helps you better understand the problems that are likely to
> arise when using phage to treat disease.MarkH
