Soonmyoung Paik, M.D.
spaik at asri.edu
Wed Feb 5 20:30:09 EST 1997
Niklas Agerhem wrote:
> Which is the most promising therapy in the immuno-field?
> Are there therapies with MOAB's that have been tested on humans.
IMHO, there are several important developments in the clinical oncology
The ones that I know are as follows;
The Genentech have been doing clinical trials for humanized antibody
against HER-2 (30% of breast cancer overexpress HER2) and got extremely
promising results (more than 10% response in advanced breast cancer with
HER-2 overexpression) and are in the process of conducting large phase
Ken Foone's group has demonstrated that anti-idiotype vaccination for
CEA could break immune tolerance against this oncofetal or tumor
hope this helps.
Soon Paik, M.D.
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