John Cherwonogrodzky jcherwon at
Fri Feb 7 10:27:06 EST 1997

Dear Colleagues:
     I'm a bacteriologist, not an immunologist and certainly not an 
oncologist.  Please excuse my ignorance but the topic of cancer antigens has 
been raised. Tom Thatcher replied that it might be possible to surgically 
remove a tumour, then make an immunostimulatory construct and 
inject this back in. Although he had some reservations on this, it got me 
thinking: Could one surgically remove a tumour, extract antigens either 
specific or more expressed on the cancer cells, inject this with an adjuvant 
or immuno-stimulatory agent, and then initiate a type of tissue rejection 
cascade to eliminate any secondary tumours?
     Take care...John

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