CD5+ b-lymphcyttes and immunity to polysaccharides

Tor A Strand torstr at
Wed Jan 22 08:19:03 EST 1997

Adults have mostly CD5-  b-lymphocyttes, but before the age of 2 a lot of
b - lymphocyttes are CD5+. Is it so that CD5- lymphocyttes are better than
the other in mounting a immunresponse agains a t-cell independent antigen
like a pneumococcal polysaccharide.

Does anybody know what regulates these populations and the maturation of
b- cells.

How good does the population of lymphocyttes in the spleen reflect the
population in the blood?

Tor A Strand
Centre of International Health
University of Bergen 

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