IUBio

angioedema

Bob Scibienski rjscibienski at ucdavis.edu
Wed Jul 2 17:17:07 EST 1997


elmurd at NAVPOINT.COM (Elanor Murdock) wrote:

>I am looking for any connection between angioedema onset and brown 
>recluse spider bite.  eleanor

Any event which results in expoxure of the blood plasma to the protein layer
which underlies the cellular lining of the blood vessels can trigger episodes of
angioedema.  Even tiny lacerations can be at fault if the C1INH deficiency is
severe enough.  Also, I don't know the details of brown recluse venom but if it
contains any proteases (which is likely) then these also could potentially
trigger an episode.

Bob S.




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