I find in a french book : Pastoret, Govaerts, Bazin : Immunolgie animale,
1990 edition Flammarion Medecin/Sciences :
rats housed in SPF conditions : (mg/ml) IgM : 0.90 - IgD : 0 - IgG1 : 0.65
- IgG2a : 1.17 - IgG2b : 0.96 - IgG2c : 2.51 - IgE : 0 - IgA : 0.03
rats housed in conventional conditions : IgM : 0.83 - IgD : 0.008 - IgG1 :
1.48 - IgG2a : 2.38 - IgG2b : 2.61 - IgG2c : 1.40 - IgE : 0.0001 - IgA :
0.05
I think it could help you and if you want more details, I've got the
book...
Rick Bungiro a écrit dans l'article ...
>Hi folks!
>>I have recently been immunizing rats with parasite antigens and
>evaluating the isotype distribution of the Ag-specific antibodies
>produced. I got to thinking that it might be good to know the normal
>level of each isotype (e.g. IgM, IgG1, IgG2a, etc.) in rat serum, but I
>have been unable to locate this information. I have tried various
>immunology textbooks (where info is readily available for mouse and human
>antibodies), Medline searches, asking a D.V.M., etc. About the best I
>could find was info on the total concentration of gamma globulin in rat
>serum - not quite specific enough.
>>Could anybody out there point me to a reference?
>>Rick Bungiro
>
