re-posting because seems in danger of drifting into newsgroup
backwaters this weekend, before knowledgeable people see it.
In <5q48l9$1vo at dfw-ixnews9.ix.netcom.com> flefever at ix.netcom.com(F.
Frank LeFever) writes:
>>IL-1 is involved in various painful conditions, and in direct
>application (of exogenous IL-1) seems to have a biphasic effect on
pain
>mechanisms, but I want to ask the question the other way around:
>>Does anyone know of evidence for IL-1 production being stimulated by
>pain? i.e., not by something messy, like an infection which with or
>without accompanying pain would elicit it, but by neat, aseptic pain,
>e.g. by electric shock or thermal stimulation?
>>Considering the many "non-immunological" things which can stimulate it
>(e.g. restraint stress), it seems a likely possibility--but do you
know
>of any direct evidence?
>>I'm especially interested in production in brain sites, but will
gladly
>look at studies of peripheral IL-1 production.
>>Frank LeFever FAX (914) 947-3350
>New York Neuropsychology Group flefever at ix.netcom.com>
