Postdoctoral fellow positions for applicants with experience in
immunology and virology are available. Our research focuses on
molecular and immunological aspects of viral pathogenesis and on the
mechanisms govern the development and regulation of antiviral T and B
cells. In particular, we are interested in understanding how viruses
are eliminated or persist in the infected host. We will also study at
the molecular level of the immunopathogenic role played by individual
cytokines in viral infections.
As our understanding of these issues has been significantly
advanced through the use of transgenic or gene-targeting mouse
technology, we use in our experimental design different sets of mice as
follows: (a) transgenic mice expressing particular antiviral T cell
receptors or viral structural proteins and (b) knock-out mice lacking
characteristic immunological molecules or deficient in cytokines. Thus,
we have developed a model using antiviral T cell receptor transgenic
mice to study the pathological process in the lungs following influenza
A viral infection. Another model aims to analyze viral persistence in
mice infected with lymphocytic choriomeningitis virus (LCMV).
My laboratory is located in the new Institute of Molecular
Medicine and Genetics at the Medical College of Georgia.
Candidates apply to Demetrius Moskophidis,
Institute of Molecular Medicine & Genetics
Medical College of Georgia
1120 15th street, CB-2803
Augusta, Georgia 30912-3175
Phone (706) 721-8738
Fax. (706) 721 8732
e-mail: moskophidis at immag.mcg.edu
