Sulfate vs sulfa vs "s" allergy

bruce R Bruck at
Thu Aug 20 15:15:28 EST 1998

We often get the following question?
I a patient is allergic to a sulfonamide containing antibiotic can the
patient take a medication sith sulfate in the name.  IE morphine sulfate,
magneesium sulfate.

I always tell peopl that sulfate is a different structure from that of a
sulfonamide and that no cross reaction is expected because the patient is
not allergic to "s" but the compound itself.

Has anyone ever seen this written any where or a written explanation for
this.  I would like to see it documented in an article or somthing so that
other people do not think I am crazy.

If you ave any info please e-mail me at Bruck at

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