How to detect pyridinoline?

Jackson Lai hsjackson at
Wed Jan 21 01:44:14 EST 1998

Dear everybody,

    I am a research student studying the formation of hypertrophic scar
after themo-injury. I have some question want to ask :

    Beside HPLC and ELISA, how can I detect the level of pyridioline (a
collagen cross linkage form by 3 amino acid) ?

    How can I raise antibodies against this small molecule?

    Any good references can help me in this field?

    Thank a lot.

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