question: monoclonal lymphocyte populations

cseabra at mail.telepac.pt cseabra at mail.telepac.pt
Thu Nov 5 13:05:59 EST 1998



I would like to know about the extent of normal immune responses.

The question is this:

if, in a patient of yours, you find in the periferal blood and in the
bone marrow a monoclonal population of lymphocytes, how many of them are
enought for you to consider the finding abnormal. We found a monoclonal B cell
population in pb-3% and bm-5% in a male 67 years old patient.

Are there completely monoclonal immune responses?
Can the more frequent epitopes in a normal immune response be present in
such numbers as to be mistaken for a neoplasic cell line?

I think not but I´m not sure.


-----------== Posted via Deja News, The Discussion Network ==----------
http://www.dejanews.com/       Search, Read, Discuss, or Start Your Own    



More information about the Immuno mailing list