EBV equivalent for mice?

Bernard P. Murray, PhD bpmurray*STUFFER* at socrates.ucsf.edu
Sat Nov 28 17:33:10 EST 1998


In article <73pu5b$j5j at pmgm.Stanford.EDU>, jladasky at pmgm.Stanford.EDU
(John Ladasky) wrote:

> Hi there,
> 
>         In our laboratory we often use Epstein-Barr virus (EBV) to create
> immortalized primate B cell cultures in vitro.  I was wondering if there
> exist similar viruses that are known to transform mouse cells.  Anyone
> know?  Thanks!

I believe that polyoma virus will do this (but I'm no virologist
so you had better check).  If I remember correctly only a small
number of genes (?large T, ?middle T) are required.
     I hope that this is a start,
          Bernard
-- 
Bernard P. Murray, PhD
Dept. Cell. Mol. Pharmacol., UCSF, San Francisco, USA



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