"AIDS Treatment News" online * New Issue #302 (searchable/indexed)

johnburgin at worldnet.att.net johnburgin at worldnet.att.net
Sat Oct 3 13:16:40 EST 1998

On Sat, 03 Oct 1998 12:29:21 GMT, f.raaphorst at worldonline.nl wrote:

>In article <36155a63.88553199 at netnews.worldnet.att.net>,
>  johnburgin at worldnet.att.net wrote:
>> On Fri, 02 Oct 1998 14:46:51 -0700, marnix at u.washington.edu (Marnix L.
>> Bosch) wrote:
>> >In article <361545cd.83282293 at netnews.worldnet.att.net>,
>> >johnburgin at worldnet.att.net wrote:
>> >
>> >
>> >> >If you knew anything about the field that you blather on about,
>> >> >you would know that proteases are virtually never prescribed without
>> >> >*2* drugs from AZT's class (nucleoside analogue reverse transcriptase
>> >> >inhibitors) The most commonly prescribed protease-containing regimens
>> >> >consist of AZT, 3TC, and a protease. That is one thing I have never
>> >> >seen any "dissident" be able to explain. If AZT is so toxic, how come
>> >> >combining it with another drug in it's class, and a protease causes
>> >> >death rates to drop in clinical endpoint trials?
>> >
>> >> The short answer or the long one?  I prefer the short.  Less AZT
>> >> combined with anything else in the PI category means less toxicity.
>> >> Why is that so confusing?  Am I missing something, do you contend that
>> >> the same amounts of AZT are given "with" PI "therapy" as "recommended"
>> >> alone?  There you have it, a "dissident "explains".jb
>> >
>> >Thanks for this testimony of ignorance. I'll give you a chance to correct
>> >it though. Please post data showing that AZT in combo therapy is given in
>> >lower doses than used in monotherapy. If those data show the doses are no
>> >different, then please address the question again.
>> Marnix,  people are living longer without the dosages of AZT as before
>> the era of the PI's for "AIDS" therapy.  Just check out the declining
>> death rates,  your choice, CDC, NIH, whatever.  Answer the question,
>> are AZT dosages less in combined therapy than when AZT was prescribed
>> alone?  Can't handle this one, Herr Marnix?  jb
>Just answer the question jb, not this evasive stuff.
>Come on, we're waiting.
you first.  It's the same kind of question, a trap.  All you have to
do is answer "yes or no".   jb
>Frank Raaphorst
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