"AIDS Treatment News" online * New Issue #302 (searchable/indexed)

f.raaphorst at worldonline.nl f.raaphorst at worldonline.nl
Sat Oct 3 07:29:21 EST 1998

In article <36155a63.88553199 at netnews.worldnet.att.net>,
  johnburgin at worldnet.att.net wrote:
> On Fri, 02 Oct 1998 14:46:51 -0700, marnix at u.washington.edu (Marnix L.
> Bosch) wrote:
> >In article <361545cd.83282293 at netnews.worldnet.att.net>,
> >johnburgin at worldnet.att.net wrote:
> >
> >
> >> >If you knew anything about the field that you blather on about,
> >> >you would know that proteases are virtually never prescribed without
> >> >*2* drugs from AZT's class (nucleoside analogue reverse transcriptase
> >> >inhibitors) The most commonly prescribed protease-containing regimens
> >> >consist of AZT, 3TC, and a protease. That is one thing I have never
> >> >seen any "dissident" be able to explain. If AZT is so toxic, how come
> >> >combining it with another drug in it's class, and a protease causes
> >> >death rates to drop in clinical endpoint trials?
> >
> >> The short answer or the long one?  I prefer the short.  Less AZT
> >> combined with anything else in the PI category means less toxicity.
> >> Why is that so confusing?  Am I missing something, do you contend that
> >> the same amounts of AZT are given "with" PI "therapy" as "recommended"
> >> alone?  There you have it, a "dissident "explains".jb
> >
> >Thanks for this testimony of ignorance. I'll give you a chance to correct
> >it though. Please post data showing that AZT in combo therapy is given in
> >lower doses than used in monotherapy. If those data show the doses are no
> >different, then please address the question again.
> Marnix,  people are living longer without the dosages of AZT as before
> the era of the PI's for "AIDS" therapy.  Just check out the declining
> death rates,  your choice, CDC, NIH, whatever.  Answer the question,
> are AZT dosages less in combined therapy than when AZT was prescribed
> alone?  Can't handle this one, Herr Marnix?  jb

Just answer the question jb, not this evasive stuff.
Come on, we're waiting.

Frank Raaphorst

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