"AIDS Treatment News" online * New Issue #302 (searchable/indexed)

Carlton Hogan carlton at walleye.ccbr.umn.edu
Mon Oct 5 10:49:36 EST 1998


In article <361669aa.158010084 at netnews.worldnet.att.net>,
 <johnburgin at worldnet.att.net> wrote:
>On Sat, 03 Oct 1998 12:29:21 GMT, f.raaphorst at worldonline.nl wrote:
>
>>> >> The short answer or the long one?  I prefer the short.  Less AZT
>>> >> combined with anything else in the PI category means less toxicity.
>>> >> Why is that so confusing?  Am I missing something, do you contend that
>>> >> the same amounts of AZT are given "with" PI "therapy" as "recommended"
>>> >> alone?  There you have it, a "dissident "explains".jb
>>> >
>>> >Thanks for this testimony of ignorance. I'll give you a chance to correct
>>> >it though. Please post data showing that AZT in combo therapy is given in
>>> >lower doses than used in monotherapy. If those data show the doses are no
>>> >different, then please address the question again.

>>> Marnix,  people are living longer without the dosages of AZT as before
>>> the era of the PI's for "AIDS" therapy.  Just check out the declining
>>> death rates,  your choice, CDC, NIH, whatever.  Answer the question,
>>> are AZT dosages less in combined therapy than when AZT was prescribed
>>> alone?  Can't handle this one, Herr Marnix?  jb
>>
>>Just answer the question jb, not this evasive stuff.
>>Come on, we're waiting.
>you first.  It's the same kind of question, a trap.  All you have to
>do is answer "yes or no".   jb

The answer is "no", AZT is not generally prescribed in reduced dosage
with PIs. FDA approval, package inserts, and "expert panels", like
the IoMs and the IAS's all concur. Come back when you know something.

Carlton



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