vaccine discovery

Larry Dubov dubov at home.com
Mon Sep 14 13:37:18 EST 1998

I am trying to get some background in vaccine discovery and understand
new trends in the area.  

Specifically, what research mode is dominant and what is emerging in
drug discovery - eg brute force screening, high throughput screening,
protein structure/function analysis? Also, is there anything different
about pre-clinical work in vaccines vs therapeutics?  

I would greatly appreciate 1) Any comments on the topic, 2) Any
references to relevant surveys.



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