"Joe Chandler" <mbiotec at maine.rr.com> wrote:
>A couple of thoughts:
>1. Is it possible that the level of protein epression is now equivilent to
>the level of antibody expression. Thus, all the antibody is cleared as
>ag/ab complex.
Could they check for CICs? Or just see if the critters' kidneys are
clogged?
>Or, 2. how can you be sure that there is still expression of the viral
>antigens. Have you continued to immunize the mice with the DNA vector?
>[Curious to hear from others as we are initiating a DNA immunization
>program here.]
And what about the cell-mediated response?
George