A couple of thoughts:
1. Is it possible that the level of protein epression is now equivilent to
the level of antibody expression. Thus, all the antibody is cleared as
Or, 2. how can you be sure that there is still expression of the viral
antigens. Have you continued to immunize the mice with the DNA vector?
[Curious to hear from others as we are initiating a DNA immunization
vinsin at my-dejanews.com wrote in article
<6ut566$4il$1 at nnrp1.dejanews.com>...
>>>> Dear Friends,
>> I have been using DNA vaccine against a viral infection in a murine
> Initially I got good humoral response which is now not being generated.
>> Suggestions invited.
>> Thank you in advance.
>> -----== Posted via Deja News, The Leader in Internet Discussion ==-----
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