DNA Vaccine and Immune response

Joe Chandler mbiotec at maine.rr.com
Wed Sep 30 07:15:48 EST 1998

A couple of thoughts:
1. Is it possible that the level of protein epression is now equivilent to
the level of antibody expression.  Thus, all the antibody is cleared as
ag/ab complex.
Or, 2.  how can you be sure that there is still expression of the viral
antigens.  Have you continued to immunize the mice with the DNA vector?
[Curious to hear from others as we are initiating a DNA immunization
program here.]

vinsin at my-dejanews.com wrote in article
<6ut566$4il$1 at nnrp1.dejanews.com>...
> Dear Friends,
> I have been using DNA vaccine against a viral infection in a murine
> Initially I got good humoral response which is now not being generated.
> Suggestions invited.
> Thank you in advance.
> Vinay
> -----== Posted via Deja News, The Leader in Internet Discussion ==-----
> http://www.dejanews.com/rg_mkgrp.xp   Create Your Own Free Member Forum

More information about the Immuno mailing list

Send comments to us at biosci-help [At] net.bio.net