The danger of "Danger"

Jamie Cunliffe cunlij at my-deja.com
Sun Jun 13 07:14:04 EST 1999

In article <7jclbk$bna at sjx-ixn10.ix.netcom.com>,
  flefever at ix.netcom.com(F. Frank LeFever) wrote:
> Will this be an easy subject to search for

I've eventually got round to addressing that question.

Note that the J. Immunology ref (previously quoted) actually accedes
that excessive apoptosis is the probable trigger for aggression.

There's another ref that appeared as a letter in Nature about 1988 (?
when) that supports the (quiet) apoptosis -> tolerance thesis.

Levine JS.  Koh JS.
The role of apoptosis in autoimmunity: immunogen, antigen, and
accelerant.[Review] [100 refs]
Seminars in Nephrology.  19(1):34-47, 1999 Jan.

Ring GH.  Lakkis FG.
Breakdown of self-tolerance and the pathogenesis of autoimmunity.
[Review][88 refs]
Seminars in Nephrology.  19(1):25-33, 1999 Jan.

Meyer D.  Thorwarth M.  Otto C.  Gassel HJ.  Timmermann W.  Ulrichs K.
Thiede A.
Apoptosis of alloreactive T cells in liver allografts during tolerance
Transplantation Proceedings.  31(1-2):474, 1999 Feb-Mar.

Zhang HG.  Su X.  Liu D.  Liu W.  Yang P.  Wang Z.  Edwards CK.
Bluethmann H.  Mountz JD.  Zhou T.
Induction of specific T cell tolerance by Fas ligand-expressing antigen-
presenting cells.
Journal of Immunology.  162(3):1423-30, 1999 Feb 1.

Hackett CJ.  Dickler HB.
Immunologic tolerance for immune system-mediated diseases.
Journal of Allergy & Clinical Immunology.  103(3 Pt 1):362-70, 1999 Mar.

Takahashi T.  Kuniyasu Y.  Toda M.  Sakaguchi N.  Itoh M.  Iwata M.
Shimizu J.  Sakaguchi S.
Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic
and suppressive T cells: induction of autoimmune disease by breaking
their anergic/suppressive state.
International Immunology.  10(12):1969-80, 1998 Dec.

Scheipers P.  Reiser H.
Role of the CTLA-4 receptor in T cell activation and immunity.
Physiologic function of the CTLA-4 receptor. [Review] [93 refs]
Immunologic Research.  18(2):103-15, 1998.

Bercovici N.  Delon J.  Cambouris C.  Escriou N.  Debre P.  Liblau RS.
Chronic intravenous injections of antigen induce and maintain tolerance
in T cell receptor-transgenic mice.
European Journal of Immunology.  29(1):345-54, 1999 Jan.

Schwarz T.
Mechanisms of UV-induced immunosuppression. Link between UV-induced
tolerance and apoptosis.
European Journal of Dermatology.  8(3):196-7, 1998 Apr-May.

Mason LJ.  Isenberg DA.
Immunopathogenesis of SLE. [Review] [51 refs]
Baillieres Clinical Rheumatology.  12(3):385-403, 1998 Aug.

Josien R.  Muschen M.  Gilbert E.  Douillard P.  Heslan JM.  Soulillou
JP. Cuturi MC.
Fas ligand, tumor necrosis factor-alpha expression, and apoptosis during
  allograft rejection and tolerance.
Transplantation.  66(7):887-93, 1998 Oct 15.

Lauritzsen GF.  Hofgaard PO.  Schenck K.  Bogen B.
Clonal deletion of thymocytes as a tumor escape mechanism.
International Journal of Cancer.  78(2):216-22, 1998 Oct 5.

Gao Y.  Herndon JM.  Zhang H.  Griffith TS.  Ferguson TA.
Antiinflammatory effects of CD95 ligand (FasL)-induced apoptosis.
Journal of Experimental Medicine.  188(5):887-96, 1998 Sep 7.

Schwarz A.  Grabbe S.  Grosse-Heitmeyer K.  Roters B.  Riemann H.
Luger TA.  Trinchieri G.  Schwarz T.
Ultraviolet light-induced immune tolerance is mediated via the Fas/Fas-
ligand system.
Journal of Immunology.  160(9):4262-70, 1998 May 1.

Kabelitz D.
Apoptosis, graft rejection, and transplantation tolerance. [Review]
[75   refs]
Transplantation.  65(7):869-75, 1998 Apr 15.


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