Replacement/Silent mutations in IgVH-genes!!!

forsdyke forsdyke at
Tue Mar 30 17:19:20 EST 1999

Constanze Knörr wrote:

> relative size of CDRs or FRs. I cannot recalculate the values given in
> the paper!
> Does anyone have the software for calculating the total possible
> mutation in a given VH-gene, like in the paper from CHang and Casali!!!

Kumar and coworkers at Penn State University put out a package called
MEGA which might be of help.  Their email is imeg at

Hope this helps,

Donald Forsdyke. "Discussion Leader" Bionet.immunology

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