Anti-MHC-peptide complex antibodies??

ladasky at ladasky at
Thu Sep 30 02:42:28 EST 1999

In article <Pine.OSF.3.91.990929165822.20662A-100000 at>,
  nsharma at IMTECH.ERNET.IN (Naresh Sharma) wrote:
> Has anybody raised antibodies against MHC-peptide complex ?
> reply to
> naresh76 at

There are many anti-MHC antibodies that recognize MHC complexed with

Or do you mean to ask whether there are antibodies against *specific*
peptides bound to *specific* MHC molecules?  Well, no, there are none of
those.  There are a few antibodies which recognize portions of the alpha
helices plus an amino acid or two of the peptide, but that's as specific
as they get.

John J. Ladasky Jr., Ph.D.
Department of Structural Biology
Stanford University Medical Center
Stanford, CA 94305

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