silent/replacement mutation

Frank Leithäuser frank.leithaeuser at
Mon Apr 17 12:49:19 EST 2000

Does anybody know how to score a mutation in terms of silent /
replacement if there are two or even three mutations in a single codon?
Is every mutation counted seperately as a replacement or silent mutation
according to whether it would have caused an amino acid replacement and
regardless of what the combined two or three mutations present in the
codon would have resulted in?

Thank you very much!

Frank Leithaeuser


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