cytokine induction by HCV peptides

[Alberto Bergamini]

Could anyone tell me which of the following HCV peptides are able to
induce cytokine production in in vitro cultured PBMC from patients with
chronic hepatitis C? Also, does anyone know how long the stimulation
period should be , using cytofluorimetric analysis as the detection
method?
Peptides:
1) core, aa. 19-25
2) core, aa. 107-174
3) E2, aa.484-499
4) NS4, aa. 1658-1863.
Thank you in advance
Alberto Bergamini, M.D.
Dept of Public Health
University of Rome

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