isotype switch in established B cell hybridoma

nan at inflam.lu.se nan at inflam.lu.se
Thu Jun 15 09:59:47 EST 2000

Dear friends,

We are interested in getting the isotype switch variants of
an established, stable B-cell hybridoma. Now, the hybridoma
secretes IgG1 antibodies. I would like to use gamma interferon
with the hybridoma to get the IgG2a antibodies.
Is there any established protocol available or possible
references? Any lead will be highly useful.

With regards,

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