mAb glycosylation

Tom Barr mdp96tab at shef.ac.uk
Fri Nov 3 05:17:58 EST 2000


Joe,
    I think you're right... phage mAbs (scFv) are un-glycosylated and are
single chains.
My mAbs are standard hybridoma produced antibodies. I've done a quick test on
them and it appears they are glycosylated.
I find it hard to  see how tyhey couldn't be. Howvere, I read in Hermansson
(Bioconjugate Techniques) that many mAbs
are un-glycosylated.... I'm not convinced.

Cheers,

Tom








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