T cell adhesion

Andrew Hall andrew.hall at virgin.net
Fri Sep 1 03:10:54 EST 2000


I wouldn't have thought so. The T-cells will bind to the Ab on the plate
rather than the plate itself, unless some of the soluble anti-CD3 becomes
bound to the plate.
When I stimulate T-cells and measure the difference in proliferation between
cells cultured for 5 days in a TC flask and those transfered to a fresh
flask from the same culture there is very lttle difference in proliferation.
If activated cells bound to the flask there would be a difference in
proliferation between the two. If you follow :)

Andrew

<vvasta at hotmail.com> wrote in message news:39ADD7DE.60883F67 at hotmail.com...
> T cells adhere to plastic coated with anti cd3 abs, I wonder if they
> adhere even when stimulated with soluble cd3  as they are activated
>
>
> ---







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