Mark Haynes Mark.Haynes at Mail.TJU.Edu
Sat Apr 7 12:45:17 EST 2001

don't ya just love this contraption!!!

Doug Neubauer wrote:

> In article <3ACC996B.CE408820 at Mail.TJU.Edu>, Mark.Haynes at Mail.TJU.Edu wrote:
> >Hello all,
> >I am looking for information about secondary markers (cd28, ctla4,
> >cd40l) on human T cells.  I want to know what differences there are
> >between virgin and non-virgin T's regarding expression.  I know that
> >ctla4 is low to negligible unless the cell is stimulated and I plan to
> >compare un-stimulated to anti-cd3 stimulated but I don't know about the
> >other molecules.
> >If someone could send refs or point me to the answers I would be
> >grateful
> >thanx
> >markH.
> >I
> >
> Not sure if this is what you're looking for,  here are some articles
> on phenotype/function vs. naive/effector/memory t cells:
> Functional differences between memory and naive CD8 T cells.,
> Cho, et al., Proc Natl Acad Sci USA 1999 Mar 16;96(6):2976-81 (PMID:10077622)
> T cell memory: heterogeneity and mechanisms.,
> Farber, Clin Immunol 2000 Jun;95(3):173-81 (PMID:10866123)
> Dynamics and requirements of T cell clonal expansion in vivo at the...,
> Gudmundsdottir, et al., J Immunol 1999 May 1;162(9):5212-23 (PMID:10227995)
> Phenotypic and functional separation of memory and effector human CD8+ T...,
> Hamann, et al., J Exp Med 1997 Nov 3;186(9):1407-18 (PMID:9348298)
> Differentiation of naive CTL to effector and memory CTL: correlation of...,
> Oehen, BrduschaRiem, J Immunol 1998 Nov 15;161(10):5338-46. (PMID:9820507)
> Regards,
> Doug
> ----------------------------------------------------------------------
> http://www.geocities.com/dougnbr

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