Can HIB shots be mixed?

PF Riley pfriley at
Wed Jan 31 01:32:57 EST 2001

On Wed, 31 Jan 2001 00:06:46 -0500, "LudwigC"
<ludwigchen at> wrote:
>We are new to the US. My son took his ACT-HIB shots when he was 5, 7 and 9
>months old. They were the same shots from the same vaccine manufacture
>"Pasteur Merieux MSD" from Lyon France. He should take his final HIB shot
>shortly. But we couldn't find the vaccine from the same manufacturer in the
>US. The US ACT-HIB vaccine is made by Aventis Pasteur in Lyon France. We
>heard that HIB shots should only be taken with the same brand for it to be
>effective because different manufactures use different formulas and
>compositions. But others say it is ok to mix brands. Even the pedestrians we
>asked said either way. We checked the two vaccines and found they had
>different compositions. We wonder if it is safe to give our son the US
>vaccine? Has anyone have this experience to share with us?

You situation is very common.

Ideally, you should complete vaccination with the same type as the
initial three doses, but in circumstances such as yours, it is not
harmful at all to use a different brand for the fourth and final dose.


More information about the Immuno mailing list