how does the body tell an exogeneous peptides from endogeneous peptides

chenhong chz155 at
Sat Aug 24 13:24:38 EST 2002

chz155 at (chenhong) wrote in message 
Thanks for your help :) chenhong

news:<2a79bee4.0208230837.4be34f19 at>...
> Hi all, 
> I have a basic immunology question to consult: how does the body tell
> exogeneous peptides from endogeneous peptides.
> I am guessing endogeneous peptides go through some modification
> process after they are synthesized. But if people know the structure
> and composition of an endogeneous peptide, then we can synthesize
> exactly such a peptide in vitro. Then how does the immune system tell
> where does this peptide come from. My second guess (wild) will be that
> the cell knows this by recalling if this peptide is swallowed or
> produced by itself.
> As you can see, I need more professional people to help me out here.
> Thanks for any help you can give me.
> Chenhong

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