Do dendritic cells move around?

John H. johnh at faraway.xxx
Thu Dec 19 01:16:20 EST 2002


I have read that microglia can differentiate into either a macrophage like
cell or a DC cell. Different CSFs is the key I think. I have also noted refs
that DCs can take up long term residence in the meninges and CNS. What I'm
confused about is whether or not those DCs in the CNS will also migrate upon
stimulation.


John H.


"Dan Marquez" <dmarquez3 at socal.rr.com> wrote in message
news:AA3M9.151067$%k2.39644340 at twister.socal.rr.com...
>
>
> "Dan Marquez" <dmarquez3 at socal.rr.com> wrote in
>
> > "When TNF, secreted by battling macrophages, binds to receptors on the
> > surface of the dendritic cell, phagocytosis ceases, and the CD leaves
the
> > tissues and migrates through the lymphatic system to the nearest lymph
> > node."
>
>
> Did I type CD?  I meant to type DC! I've been spending too much time on my
> computer!
>
> A good friend of mine brought up a interesting thought... could DC's and
> macrophages really be the same?
>
>
> Dan
>
>





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