CTL, Helper cells and B-cells etc
mark.haynes at mail.tju.edu
Wed Jan 23 12:09:09 EST 2002
"Deva Patil" <devapatil at yahoo.com> wrote in message
news:3C48D9E4.40D12DDB at yahoo.com...
> Dear All,
> I have following general questions in Immunology and would appreciate
> your attention.
> 1) Is the response of CD8+ CTL response dependent on CD4+ Helper cells?
Certainly the generation of CTL responses are dependent on helper-inducer
but whether every antigen response by CD8 cells is absolutely governed by
CD4 responses hmmm i'm sure there are model systems that show that it
ain't i just can't think of one.
> 2) If so, within the CD4+ Helper cells, is there a subpopulation
> specifically interacting with CD8+ CTLs
> and another subpopulation interacting with B cells?
-in general TH1 cells help cytotoxic reponses and Th2 cells help Ab
responses but the lines aren't solid here either.
> Thank you very much for your time.
> Deva Patil
> Oxford, UK
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