Nude mouse and lymphocytes.
mark.haynes at mail.tju.edu
Fri Jul 12 10:06:53 EST 2002
the info on this has to be out there somewhere
maybe some 80's paper where a comparative expt was done using a facs or
"Gary" <cool_and_funky at yahoo.com> wrote in message
news:b5023d22.0207110253.a566025 at posting.google.com...
> Does anyone have any idea how the nude mouse compares in terms of the
> number of lymphocytes one would expect to see in its blood? I'm aware
> that the nude mouse is for all intents and purposes athymic, meaning
> that there is a lack of immunologically mature lymphocytes and a loss
> of ability to recognise non-self cells, but does this mean that there
> would actually be a decreased overall number of lymphocytes in the
> bloodstream, or would there be an equivalent number of cells (compared
> to a immunocompetent mouse) but these cells would be effectively
> unable to elicit an immune response?
> It'd be interesting to know, as I've not managed to find anyone so far
> that can confidently answer this.
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