Will Transfer Factors Replace Vaccines?

Daniele Focosi mi at interhealth.info
Sun Jan 5 14:29:28 EST 2003


"Dan Marquez" <dmarquez3 at socal.rr.com> wrote in message news:<S4GR9.218831$%k2.60747874 at twister.socal.rr.com>...

> So true... the probability that the cytokines will bind to receptors is
> decreased in the method shown.

The method doesn't eliminate longer peptides, so 44 amino acids could
be the normal length of avian cytokines... It would be interesting to
know the length of peptides in bovine transfer factor (bovine
cytokines should be more similar to human ones) : can you find such a
patent ?
Anyway I was wrong when I wrote that there's no difference between
drinking a glass of milk and taking bovine transfer factor pills :
colostrum is produced exclusively in the first days after carriage and
hence the milk we use to drink is obviously likely not to be
colostrum.

> There are 80 (or so) known
> amino acids in the world. Yet, humans use only 20 of them. I would be
> curious if the remaining 60 amino acids are antigens to humans, and if
> animals such as chickens, cows, and mice carry any of those 60.

Basically all living organisms use the same 20 amino acids (sometimes
a little more) to translate the message in RNA into a protein : some
of them can be posttranslationally modified to create new amino acid
residues.
Most living organisms can anyway produce other amino acids (up to 80,
or so) that are neither incorporated into proteins nor appear as
result of post-translational modifications : I suppose they are about
the same even for distantly related species. Anyway amino acids are
too small to be immunogenic : they act just as haptens, i.e. they can
be immunogenic only if conjugated to a larger, immunogenic carrier
(e.g. a protein).

Daniele



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