mitogens

Eric say.no at spam.now
Sun Jun 20 17:19:48 EST 2004


> nicolleen at linuxmail.org wrote in message news:<20040615124845.7705.qmail at ww02.hostica.com>...
> hi there,
>
> can anybody tell me what the difference is between various mitogens such
> as pha/conA and pma/ionomycin? is maybe pma/ionomycin stimulating the
> cytokine expression rather than proliferating ...
>

To add to Don's information, PMA, or phorbol-12-myristate-13-acetate, is a
phorbol ester that activates protein kinase c (PKC).  Ionomycin is a
ionophore which carries Ca2+ into the cell.

Eric



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