A very good site for learning how to identify CDRs is at:
http://www.bioinf.org.uk/abs/
Allison
Ilham Omer wrote:
> Dear Mr or Madam
> can you help my identify CDRs L1L2L3and H1H2H3 for my heavy and light chain.
> thanks
> Elham
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>> light chain
> gacattgagctcacccagtctccagcaatcatgtctgcatctccaggggagagggtcacc
> D I E L T Q S P A I M S A S P G E R V T
> atgacctgcagtgccagctcaagtatacgttacatatattggtaccaacagaagcctgga
> M T C S A S S S I R Y I Y W Y Q Q K P G
> tcctcccccagactcctgatttatgacacatccaacgtggctcctggagtcccttttcct
> S S P R L L I Y D T S N V A P G V P F P
> tcantggcaatggggtctggggacctcttattctctcacaatcaaccgaatggangctga
> S X A M G S G D L L F S H N Q P N G X -
> aggatgcctgccacttattactgccaggagtggagtggttacccgtacacnttcggaggg
> R M P A T Y Y C Q E W S G Y P Y X F G G
> gggacaagctggaactgaaacg
> G T S W N - N
>> heavy chain
> gagacggtgaccgtggtcccttggccccacaagtcaaagtagcgcctatagtagtcccctct
> D G D R G P L A P Q V K V A P I V V P S
> agcacagaaatagacagcagagtcctcagatgtcagcctagtgagctccatataggctgt
> S T E I D S R V L R C Q P S E L H I G C
> gctggaggacttgtctacactcagtgtggccctgcccttgaacttctcattgtattcagt
> A G G L V Y T Q C G P A L E L L I V F S
> actcccctctccaggaaaaatccatccaatccactcaagtccctgttcaggcgtctgcct
> T P L S R K N P S N P L K S L F R R L P
> cacccagtctatatcataacttgtgaagatgtagccagaagccttgcaggacaacttcac
> H P V Y I I T C E D V A R S L A G Q L H
> tgaagccccaggctttaccacttcagttccttactgctgcagcttcacct
> - S P R L Y H F S S L L L Q L H
