IUBio

[Immunology] Re: CDRs identification

Allison allison at nospam.com
Fri Sep 29 09:11:03 EST 2006


A very good site for learning how to identify CDRs is at:

http://www.bioinf.org.uk/abs/


Allison



Ilham Omer wrote:
> Dear Mr or Madam
>   can you help my identify CDRs L1L2L3and H1H2H3 for my heavy and light chain.
>   thanks
>   Elham
> 
>  			
> ---------------------------------
> Get your own web address for just $1.99/1st yr. We'll help. Yahoo! Small Business.
> 
> 
> ------------------------------------------------------------------------
> 
> light chain
> gacattgagctcacccagtctccagcaatcatgtctgcatctccaggggagagggtcacc
>  D  I  E  L  T  Q  S  P  A  I  M  S  A  S  P  G  E  R  V  T 
> atgacctgcagtgccagctcaagtatacgttacatatattggtaccaacagaagcctgga
>  M  T  C  S  A  S  S  S  I  R  Y  I  Y  W  Y  Q  Q  K  P  G 
> tcctcccccagactcctgatttatgacacatccaacgtggctcctggagtcccttttcct
>  S  S  P  R  L  L  I  Y  D  T  S  N  V  A  P  G  V  P  F  P 
> tcantggcaatggggtctggggacctcttattctctcacaatcaaccgaatggangctga
>  S  X  A  M  G  S  G  D  L  L  F  S  H  N  Q  P  N  G  X  - 
> aggatgcctgccacttattactgccaggagtggagtggttacccgtacacnttcggaggg
>  R  M  P  A  T  Y  Y  C  Q  E  W  S  G  Y  P  Y  X  F  G  G 
> gggacaagctggaactgaaacg
>  G  T  S  W  N  -  N 
> 
> heavy chain  
> gagacggtgaccgtggtcccttggccccacaagtcaaagtagcgcctatagtagtcccctct
>    D  G  D  R  G  P  L  A  P  Q  V  K  V  A  P  I  V  V  P  S 
> agcacagaaatagacagcagagtcctcagatgtcagcctagtgagctccatataggctgt
>  S  T  E  I  D  S  R  V  L  R  C  Q  P  S  E  L  H  I  G  C 
> gctggaggacttgtctacactcagtgtggccctgcccttgaacttctcattgtattcagt
>  A  G  G  L  V  Y  T  Q  C  G  P  A  L  E  L  L  I  V  F  S 
> actcccctctccaggaaaaatccatccaatccactcaagtccctgttcaggcgtctgcct
>  T  P  L  S  R  K  N  P  S  N  P  L  K  S  L  F  R  R  L  P 
> cacccagtctatatcataacttgtgaagatgtagccagaagccttgcaggacaacttcac
>  H  P  V  Y  I  I  T  C  E  D  V  A  R  S  L  A  G  Q  L  H 
> tgaagccccaggctttaccacttcagttccttactgctgcagcttcacct
>  -  S  P  R  L  Y  H  F  S  S  L  L  L  Q  L  H   


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