Use of spermidine- how? why?
BROE at AARDVARK.UCS.UOKNOR.EDU
Fri Aug 23 08:11:00 EST 1991
According to Lehninger's Biochemistry (certa 1970 edition):
Spermidine, and other polyamines, will interact with nucleic
acids and neutralize the negative charges. The result is that the
nucleic acids will be more flexible.
Sorry for this "old" reference, but there is a large body
of literature on the effects of polyamines on nucleic acids. As
for the effects on proteins, the effect may be similar since many
proteins (especially globular proteins) have a hydrophilic exterior
and thus exposed negative charges most likely may interact with
The weather today in Oklahoma is predicted to be 93 deg., blue
skys and <30% relative humidity.
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