Mutation Detection Enhancemnt Gels

walley at vax.oxford.ac.uk walley at vax.oxford.ac.uk
Wed Feb 26 09:49:53 EST 1992


Dear netters,
		Firstly, thanks for the replies about thermostable ligase. On 
a similar tack, I have just come across an ad in Science for MDE (Mutation 
Detection Enhancement) gel. This is claimed to enhance the sensitivity of SSCP 
and Heteroduplex screening as compared to standard polyacrylamide. I have two 
questions arising from this:

	Can anyone report any practical experience with it ?

	Does anyone have the address of an English agent for AT Biochem Inc. ?

Thanks,
	Andrew J. Walley,
	Inst. of Molecular Medicine,
	Oxford,
	England.



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