Taq Ligase and LDR

walley at vax.oxford.ac.uk walley at vax.oxford.ac.uk
Mon Jan 20 12:35:37 EST 1992


Des anyone have any idea where I can obtain Taq Ligase, or any other
thermostable ligase suitable for the Ligase Detection Reaction described
by F. Barany (PNAS 88:189-193). Does anyone have any experience of this 
technique - how suitable is it for large-scale screening of a gene for 
common mutations ?

Thanks,
Andrew J. Walley,
Institute of Molecular Medicine,
John Radcliffe Hospital,
Oxford,
England.



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