No more wedge gels?

JRJ at EPAVAX.RTPNC.EPA.GOV JRJ at EPAVAX.RTPNC.EPA.GOV
Fri Jun 5 15:14:00 EST 1992


	I also used to use this technique.  My understaqnding is that the
higher ionic strength means that the resistance is lower at the bottom of
the gel, so according to Ohms Law, the local electrical field strength is
lower.  Since migration speed is a function of field strength, the DNA slows
down.

Jeff Ross
Carcinogenesis and Metabolism Branch
U.S.EPA



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