T cell epitopes

Dan Jacobson x-8453 danj at welchgate.welch.jhu.edu
Mon Sep 21 11:44:17 EST 1992


Bart Frank writes:

>It seems that I've heard mention of a program which predicts
>T cell epitopes from amino acid sequences.  Can someone
>tell me 
>1) where such a programs is available (ftp site preferred)
>(...)


Three programs which come to mind are Epiplot, Tsites, and Seqaid.
Epiplot and Tsites are programs devoted specifically for epitope
prediction, Seqaid is a general sequence utlity program with several
functions, one of which is epitope prediction.  Seqaid and Epiplot are
for PCs (DOS), Tsites has a Mac version and probably a DOS version.

You can ftp Epiplot from:

Host evolution.bchs.uh.edu

    Location: /pub/gene-server/dos
           FILE -rwxr--r--     129317  Sep 16 1991  epiplot.uue



You can ftp seqaid from:

Host fly.bio.indiana.edu

    Location: /molbio/ibmpc
           FILE -rw-r--r--     324175  May 14 1991  seqaidfd.uue

Host genbank.bio.net

    Location: /pub/dos
           FILE -rw-rw-r--       6167  Oct 26 1989  seqaid.doc
           FILE -rw-rw-r--     324175  Jul 14 1989  seqaidfd.uue

Host nic.funet.fi

    Location: /pub/sci/molbio/msdos
           FILE -rw-r--r--     251259  Feb  3 00:00  seqaid.exe
           FILE -rw-rw-r--     305448  Jun 23 1991  seqaid37.shar
           FILE -rw-r--r--      73370  Feb  3 00:00  seqaidfd.exe


There is no ftp site for Tsites that I know of, you can obtain it
for free by writing to:

MedImmune, Inc
19 Firstfield Rd.
Gaithersburg, MD 20878  (USA)




Kudos go to the authors and Dan Davison, Don Gilbert and Rob Harper for the
ftp sites.




Best of luck,

Dan Jacobson



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