MMT or TFA Amine Linkers for Oligos?

Russ Herwig herwig at u.washington.edu
Tue Jul 6 19:29:34 EST 1993


MilliGen/Biosearch sells two kinds of amine linkers for oligos:
			N-TFAc-Hexanolamine Linker
			N-MMT-Hexamolamine Linker

The TFA linker is base labile, and the MMT linker is acid labile.  Any
major advantage (or disadvantage) to using one of the linkers, or is it a
toss-up?

Russ Herwig
Department of Microbiology SC-42
University of Washington
Seattle, WA  98195



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