csax at helix.nih.gov
Thu Jun 3 12:05:00 EST 1993
In article <9305310721.AA06035 at cscgpo.anu.edu.au> Klaus.Matthaei at anu.edu.au writes:
>>Dear Immunologists or anyone else for that matter,
>>I have a very quick two part question, that I would be very happy if someone
>>could give me some advice on.
>>What is the average size of a linear epitope that is recognized by a monoclonal
>>Ab, and secondly, is an epitope size of 10 amino acids typically unheard of?
>>Thanks in advance for any suggestions.
>>botdjl at lure.latrobe.edu.au
>I do not consider myself as a immunologist but in my darkest memory the
>smallest epitope that seems to raise from my past I thought was about 8
>amino acids but I couldn't give a reference.
>I will also be happy to haer opinions.
We have determined one of the antibody epitopes of the HTLV1 envelope
glycoprotein to be three amino acids. Many others have been found to
be 8 or less.
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