CTG as a start codon

mazella mazella at naxos.unice.fr
Fri Aug 19 06:52:34 EST 1994

>Hello netters
>Does anyone out there know if CTG can be used as a start codon instead of A=
>GTG or TTG.

CTG has been described as start codon for several protooncogenes
(myc,int-2,pim-1 and lyl-1) and for fribroblast growth factor gene.
You can find informations about proximal sequence's importance for this
"exotic" start codon in Boeck,R. et al., EMBO (1994) 13,3608-3617.

good luck

Institut de pharmacologie mol=E9culaire et cellulaire
660, route des lucioles
06560 valbonne
Tel n=B0:19 (33)-93-95-77-61
Tel n=B0:19 (33)-93-95-77-08
e-mail :mazella at naxos.unice.fr

More information about the Methods mailing list