HLA-DQ typing

Wachara Kasinreak watchara at CMU.CHIANGMAI.AC.TH
Tue Aug 23 21:28:35 EST 1994

Dear netters;
I am working on HLA typing in Leprosy using PCR-based DNA typing 
technique. However, I have 2 questions as follows
1.HLA-DQ genes of heterozygous individual which express 4 distrinct DQ 
molecules, why in serological typing can define only 2 DQ antigens?
2. What is the property of MT-1 antisera? what is the amino acid binding 
region on HLA_DQw1 antigen which is specific to the MT-1 antibody.

Thanks in advance

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