Antisense oligos

Dr. C.P. Healy chealy at
Fri Aug 26 07:28:22 EST 1994

I am planning some antisense experiments and need some information about oligo
design. What I need to know primarily is "Is it necessary for the antisense
site to be at the 5' cap of the mRNA?" If not, are there any other factors which

are important when designing antisense experiments? Semd replies to me and I'll
post if we get enough info. Thanks -Chris
Dr. Chris Healy,
Department of Craniofacial Development,
Guy's Hospital,
e-mail: Chris Healy <chealy at>
Tel: 071- 955-4782
Fax: 071- 955-2704

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