Induction by macromolecs

[Louis Hom]

So, there are plenty of examples where a small molecule induces the expression
of a gene, say the gene encoding the degradative enzyme.  But does anyone
know of a case where a macromolecule induces the expression of a gene?  I
realize that txn factors are macromolecules, but what I'm looking for is
induction by the presence of macromolecues besides txn factors.  (I'm looking
at virus-host interxns)
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Lou Hom		     		"Fewer things are harder to put up with than 
lhom at ocf.berkeley.edu		 the annoyance of a good example." - Mark Twain